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Clinical Depression: Signs, Symptoms, and Treatment

Clinical Depression has several stages. While a person may get depressed for a week or two, sometimes it can go till months. At the initial phases, a depressed person can overcome their depression by own through self-care, or with friends. But when it reaches major depression, it becomes necessary to take professional therapy or treatment. 

What is clinical depression or major depression?

Major depressive disorder (MDD) or clinical depression is a state of mind wherein a person constantly has the feeling of hopelessness and despair. You lose interest over the day to day activity, which affects various areas of life, like your workplace or relationship.

In the most critical case, a clinically depressed patient feels that life is not worth living. Hence, they end up committing suicides. Although clinical depression is entirely treatable, many of the patients refuse to do the treatment. You can either go for medication or psychotherapy if you feel any of the below signs and symptoms.

Signs and symptoms of clinical depression:

If you are going for medication or therapy, your doctor will ask you specific symptoms, and they will diagnose you based on it. Always mention every little behavior change, symptoms, and feelings to get the right treatment. 

It is mandatory to have below given symptoms for at least two weeks before you go for clinical depression treatment

Concentration problems: You will be facing concentration problems for more than two weeks. It will become hard for you to focus on your workplace or any other activity. You will lose interest and pleasure while doing your favorite thing. 

Insomnia: early awakening, restless sleep, or excess sleeping are some of the significant signs of clinical depression. Insomnia is common in most of the cases, due to hyper thinking the patient does not get a sound sleep for months.

Feelings of guilt: You will blame yourself for every little situation. If something terrible happens with your closed ones, then you will continuously criticize your own self. Also, you might get irritated because of this feeling, which can lead to hyper depression.

Digestive problems: Because of constant overthinking and lack of sleep, you will face poor appetite. This can even cause excessive hunger problems. You either gain weight dramatically or lose weight. 

Suicidal thoughts: As you will face constant irritation, discontent, and restlessness throughout the day, you will often get suicidal thoughts. It becomes hard for you to overcome this thought because you lose control over your emotions. 

Agitation: You always feel troubled and nervous while doing the simplest task. 

Social isolation: When in depression, you will isolate yourself from people, even if they are close to you. It will affect your self-esteem a lot.

What triggers clinical depression?

There is no specific reason behind one facing clinical depression. A person can get into significant depression when they avoid mild phases. But certain conditions increase the risk of developing a major depressive disorder.

Sometimes it is because of the constant stress or genes which effects the brain capacity to maintain mood stability. 

Women can face depression because of menstruation, as there are lots of mood swings, and the pain becomes unbearable too. Teenagers will face depression because of a change in hormones. Other triggers of clinical depression we have found in most of the cases are as follows: 

  • Continuous alcohol intake or addiction to drugs
  • Critical mental condition like high blood pressure, thyroid or cancer
  • Steroids medication
  • Society and other external factors

What are the different clinical depression treatments?

When a person goes in hyper depression, and they tend to do activities that can cause them harm, then they are suggested to go for complete medication along with therapies. 

Clinical depression requires both medication and therapy because the person is volatile, and they get suicidal thoughts at any hour of the day. There are also outpatient treatment programs done for major depression to get good results.


Doctors often prescribe antidepressants for clinical depression treatment. The most common among all is the Selective serotonin reuptake inhibitors, which help to slow down the breakdown of serotonin in the patient’s brain. 

Serotonin chemical is used to improve the mood and sleeping pattern of any individual. Once a patient goes through clinical depression, their serotonin level decreases dramatically; hence, this depressant works like wonder. 

While in pregnancy, most of the women can get affected by these antidepressants. So, to be on a safer side, it is suggested to go for psychotherapy.


Psychotherapy is one of the effective ways to treat clinical depression. It does not have any side effects, and also it gives mental support to the patient. 

If you choose psychotherapy for clinical depression, then you are required to visit the therapist according to the appointments. However, take the utmost care that you speak out every symptom and signs of major depression to your therapist. 

There are many benefits of choosing psychotherapy over medication, as you will get replace negative thoughts with positive ones. You will see your communication skills and self-esteem improved. Also, you will be able to cope up with critical challenges and solve problems on your own in the future.


Apart from medication and psychotherapy, self-care is a must when it comes to clinical depression. Hence, try to do the following regularly to ease your depression:

  • Start eating nutritious food
  • Avoid junks at any cost
  • Avoid alcohol and drug consumption
  • Do meditation 
  • Follow routine exercising
  • Get proper sleep

Is clinical depression preventable?

Yes, it can be avoided or prevented at the early stages of depression itself. If you find yourself getting depressive thoughts, then try to be outspoken about it, and talk to someone who will genuinely listen to you. 

However, if you are facing clinical depression, then do remember that it can be treated successfully. All you have to do is surround yourself with people who would actually care for you and stay with you when you are getting suicidal thoughts. Stick to your treatment plan strictly and never miss a session with your therapist!

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